Incubator Accessories
Diagnostic Biosystems PERMABLACK/HRP PermaBlack/HRP
PermaBlack/HRP is a substrate-chromogen system designed to be used for either IHC or ISH when utilizing horseradish peroxidase. PermaBlack/HRP can be permanently mounted to produce a sharply contrasting ebony black color that can be easily distinguished from other stains.
Diagnostic Biosystems PERMARED/AP PermaRed/AP
PermaRed/AP is a substrate-chromogen system designed to be used for either IHC or ISH when using alkaline phosphatase detection. PermaRed/AP produces a brilliant dark red color. PermaRed/AP is insoluble in organic solvents; therefore, sections can be dehydrated in alcohol, cleared in xylene (or a xylene-substitute), and permanently mounted. This chromogen substrate system may be used for both automation and manual use.
Diagnostic Biosystems TNF-ALPHA TNF-Alpha (Tumor Necrosis Factor alpha)
This MAb recognizes human 17-26kDa protein, which is identified as cytokine TNF-α (Tumor Necrosis Factor-alpha). Monomeric human TNF-α is a 157 amino acid protein (non-glycosylated) with a reported molecular weight of 17 kDa and can be expressed as a free molecule, also TNF-α is generated as a precursor form called transmembrane TNF-α can be expressed as a cell surface type II polypeptide consisting of 233 amino acid residues molecular weight 26 kDa. TNF-α is an important cell-signaling component of the immune system. It is a protein secreted by LPS stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF-α is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Diagnostic Biosystems LBA1 Iba1 (AIF1)
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).\n
